:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-intact' .. highlight: bash bioconductor-intact =================== .. conda:recipe:: bioconductor-intact :replaces_section_title: :noindex: Integrate TWAS and Colocalization Analysis for Gene Set Enrichment Analysis :homepage: https://bioconductor.org/packages/3.18/bioc/html/INTACT.html :license: GPL-3 + file LICENSE :recipe: /`bioconductor-intact `_/`meta.yaml `_ This package integrates colocalization probabilities from colocalization analysis with transcriptome\-wide association study \(TWAS\) scan summary statistics to implicate genes that may be biologically relevant to a complex trait. The probabilistic framework implemented in this package constrains the TWAS scan z\-score\-based likelihood using a gene\-level colocalization probability. Given gene set annotations\, this package can estimate gene set enrichment using posterior probabilities from the TWAS\-colocalization integration step. .. conda:package:: bioconductor-intact |downloads_bioconductor-intact| |docker_bioconductor-intact| :versions: ``1.2.0-0``,  ``1.0.1-0`` :depends r-base: ``>=4.3,<4.4.0a0`` :depends r-bdsmatrix: :depends r-numderiv: :depends r-squarem: :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install bioconductor-intact and update with:: mamba update bioconductor-intact To create a new environment, run:: mamba create --name myenvname bioconductor-intact with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/bioconductor-intact: (see `bioconductor-intact/tags`_ for valid values for ````) .. |downloads_bioconductor-intact| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-intact.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-intact :alt: (downloads) .. |docker_bioconductor-intact| image:: https://quay.io/repository/biocontainers/bioconductor-intact/status :target: https://quay.io/repository/biocontainers/bioconductor-intact .. _`bioconductor-intact/tags`: https://quay.io/repository/biocontainers/bioconductor-intact?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-intact/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-intact/README.html