:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-plsdabatch' .. highlight: bash bioconductor-plsdabatch ======================= .. conda:recipe:: bioconductor-plsdabatch :replaces_section_title: :noindex: PLSDA\-batch :homepage: https://bioconductor.org/packages/3.20/bioc/html/PLSDAbatch.html :license: GPL-3 :recipe: /`bioconductor-plsdabatch `_/`meta.yaml `_ A novel framework to correct for batch effects prior to any downstream analysis in microbiome data based on Projection to Latent Structures Discriminant Analysis. The main method is named “PLSDA\-batch”. It first estimates treatment and batch variation with latent components\, then subtracts batch\-associated components from the data whilst preserving biological variation of interest. PLSDA\-batch is highly suitable for microbiome data as it is non\-parametric\, multivariate and allows for ordination and data visualisation. Combined with centered log\-ratio transformation for addressing uneven library sizes and compositional structure\, PLSDA\-batch addresses all characteristics of microbiome data that existing correction methods have ignored so far. Two other variants are proposed for 1\/ unbalanced batch x treatment designs that are commonly encountered in studies with small sample sizes\, and for 2\/ selection of discriminative variables amongst treatment groups to avoid overfitting in classification problems. These two variants have widened the scope of applicability of PLSDA\-batch to different data settings. .. conda:package:: bioconductor-plsdabatch |downloads_bioconductor-plsdabatch| |docker_bioconductor-plsdabatch| :versions: ``1.2.0-0`` :depends bioconductor-biobase: ``>=2.66.0,<2.67.0`` :depends bioconductor-biocstyle: ``>=2.34.0,<2.35.0`` :depends bioconductor-mixomics: ``>=6.30.0,<6.31.0`` :depends bioconductor-treesummarizedexperiment: ``>=2.14.0,<2.15.0`` :depends r-base: ``>=4.4,<4.5.0a0`` :depends r-ggplot2: :depends r-ggpubr: :depends r-gridextra: :depends r-lmertest: :depends r-performance: :depends r-pheatmap: :depends r-rdpack: :depends r-scales: :depends r-vegan: :requirements: :additional platforms: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install bioconductor-plsdabatch and update with:: mamba update bioconductor-plsdabatch To create a new environment, run:: mamba create --name myenvname bioconductor-plsdabatch with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/bioconductor-plsdabatch: (see `bioconductor-plsdabatch/tags`_ for valid values for ````) .. |downloads_bioconductor-plsdabatch| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-plsdabatch.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-plsdabatch :alt: (downloads) .. |docker_bioconductor-plsdabatch| image:: https://quay.io/repository/biocontainers/bioconductor-plsdabatch/status :target: https://quay.io/repository/biocontainers/bioconductor-plsdabatch .. _`bioconductor-plsdabatch/tags`: https://quay.io/repository/biocontainers/bioconductor-plsdabatch?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-plsdabatch/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-plsdabatch/README.html