:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-stdeconvolve' .. highlight: bash bioconductor-stdeconvolve ========================= .. conda:recipe:: bioconductor-stdeconvolve :replaces_section_title: :noindex: Reference\-free Cell\-Type Deconvolution of Multi\-Cellular Spatially Resolved Transcriptomics Data :homepage: https://bioconductor.org/packages/3.18/bioc/html/STdeconvolve.html :license: GPL-3 :recipe: /`bioconductor-stdeconvolve `_/`meta.yaml `_ STdeconvolve as an unsupervised\, reference\-free approach to infer latent cell\-type proportions and transcriptional profiles within multi\-cellular spatially\-resolved pixels from spatial transcriptomics \(ST\) datasets. STdeconvolve builds on latent Dirichlet allocation \(LDA\)\, a generative statistical model commonly used in natural language processing for discovering latent topics in collections of documents. In the context of natural language processing\, given a count matrix of words in documents\, LDA infers the distribution of words for each topic and the distribution of topics in each document. In the context of ST data\, given a count matrix of gene expression in multi\-cellular ST pixels\, STdeconvolve applies LDA to infer the putative transcriptional profile for each cell\-type and the proportional representation of each cell\-type in each multi\-cellular ST pixel. .. conda:package:: bioconductor-stdeconvolve |downloads_bioconductor-stdeconvolve| |docker_bioconductor-stdeconvolve| :versions: ``1.2.0-0`` :depends bioconductor-biocparallel: ``>=1.32.0,<1.33.0`` :depends r-base: ``>=4.2,<4.3.0a0`` :depends r-clue: :depends r-ggplot2: :depends r-liger: :depends r-matrix: :depends r-mgcv: :depends r-reshape2: :depends r-scatterpie: :depends r-slam: :depends r-topicmodels: :depends r-viridis: :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install bioconductor-stdeconvolve and update with:: mamba update bioconductor-stdeconvolve To create a new environment, run:: mamba create --name myenvname bioconductor-stdeconvolve with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/bioconductor-stdeconvolve: (see `bioconductor-stdeconvolve/tags`_ for valid values for ````) .. |downloads_bioconductor-stdeconvolve| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-stdeconvolve.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-stdeconvolve :alt: (downloads) .. |docker_bioconductor-stdeconvolve| image:: https://quay.io/repository/biocontainers/bioconductor-stdeconvolve/status :target: https://quay.io/repository/biocontainers/bioconductor-stdeconvolve .. _`bioconductor-stdeconvolve/tags`: https://quay.io/repository/biocontainers/bioconductor-stdeconvolve?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-stdeconvolve/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-stdeconvolve/README.html