:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-synapsis' .. highlight: bash bioconductor-synapsis ===================== .. conda:recipe:: bioconductor-synapsis :replaces_section_title: :noindex: An R package to automate the analysis of double\-strand break repair during meiosis :homepage: https://bioconductor.org/packages/3.18/bioc/html/synapsis.html :license: MIT + file LICENSE :recipe: /`bioconductor-synapsis `_/`meta.yaml `_ Synapsis is a Bioconductor software package for automated \(unbiased and reproducible\) analysis of meiotic immunofluorescence datasets. The primary functions of the software can i\) identify cells in meiotic prophase that are labelled by a synaptonemal complex axis or central element protein\, ii\) isolate individual synaptonemal complexes and measure their physical length\, iii\) quantify foci and co\-localise them with synaptonemal complexes\, iv\) measure interference between synaptonemal complex\-associated foci. The software has applications that extend to multiple species and to the analysis of other proteins that label meiotic prophase chromosomes. The software converts meiotic immunofluorescence images into R data frames that are compatible with machine learning methods. Given a set of microscopy images of meiotic spread slides\, synapsis crops images around individual single cells\, counts colocalising foci on strands on a per cell basis\, and measures the distance between foci on any given strand. .. conda:package:: bioconductor-synapsis |downloads_bioconductor-synapsis| |docker_bioconductor-synapsis| :versions: ``1.8.0-0``,  ``1.6.0-0``,  ``1.4.0-0``,  ``1.0.0-0`` :depends bioconductor-ebimage: ``>=4.44.0,<4.45.0`` :depends r-base: ``>=4.3,<4.4.0a0`` :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install bioconductor-synapsis and update with:: mamba update bioconductor-synapsis To create a new environment, run:: mamba create --name myenvname bioconductor-synapsis with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/bioconductor-synapsis: (see `bioconductor-synapsis/tags`_ for valid values for ````) .. |downloads_bioconductor-synapsis| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-synapsis.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-synapsis :alt: (downloads) .. |docker_bioconductor-synapsis| image:: https://quay.io/repository/biocontainers/bioconductor-synapsis/status :target: https://quay.io/repository/biocontainers/bioconductor-synapsis .. _`bioconductor-synapsis/tags`: https://quay.io/repository/biocontainers/bioconductor-synapsis?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-synapsis/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-synapsis/README.html