:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'r-numbat' .. highlight: bash r-numbat ======== .. conda:recipe:: r-numbat :replaces_section_title: :noindex: A computational method that infers copy number variations \(CNVs\) in cancer scRNA\-seq data and reconstructs the tumor phylogeny. \'numbat\' integrates signals from gene expression\, allelic ratio\, and population haplotype structures to accurately infer allele\-specific CNVs in single cells and reconstruct their lineage relationship. \'numbat\' can be used to\: 1. detect allele\-specific copy number variations from single\-cells\; 2. differentiate tumor versus normal cells in the tumor microenvironment\; 3. infer the clonal architecture and evolutionary history of profiled tumors. \'numbat\' does not require tumor\/normal\-paired DNA or genotype data\, but operates solely on the donor scRNA\-data data \(for example\, 10x Cell Ranger output\). Additional examples and documentations are available at \. For details on the method please see Gao et al. Nature Biotechnology \(2022\) \. :homepage: https://github.com/kharchenkolab/numbat/, https://kharchenkolab.github.io/numbat/ :license: MIT / MIT :recipe: /`r-numbat `_/`meta.yaml `_ .. conda:package:: r-numbat |downloads_r-numbat| |docker_r-numbat| :versions: ``1.4.2-0`` :depends bioconductor-genomicranges: ``>=1.58.0,<1.59.0a0`` :depends bioconductor-ggtree: ``>=3.14.0,<3.15.0a0`` :depends bioconductor-iranges: ``>=2.40.0,<2.41.0a0`` :depends libgcc: ``>=13`` :depends libstdcxx: ``>=13`` :depends r-ape: :depends r-base: ``>=4.4,<4.5.0a0`` :depends r-catools: :depends r-data.table: :depends r-dendextend: :depends r-dplyr: ``>=1.1.1`` :depends r-ggplot2: :depends r-ggraph: :depends r-glue: :depends r-hahmmr: ``>=1.0.0,<1.1.0a0`` :depends r-igraph: :depends r-logger: :depends r-magrittr: :depends r-matrix: :depends r-optparse: :depends r-paralleldist: :depends r-patchwork: :depends r-pryr: :depends r-purrr: :depends r-r.utils: :depends r-rcpp: :depends r-rcpparmadillo: :depends r-rhpcblasctl: :depends r-roptim: :depends r-scales: :depends r-scistreer: ``>=1.1.0`` :depends r-scistreer: ``>=1.2.0,<1.3.0a0`` :depends r-stringr: :depends r-tibble: :depends r-tidygraph: :depends r-tidyr: ``>=1.3.0`` :depends r-vcfr: :depends r-zoo: :requirements: :additional platforms: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install r-numbat and update with:: mamba update r-numbat To create a new environment, run:: mamba create --name myenvname r-numbat with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/r-numbat: (see `r-numbat/tags`_ for valid values for ````) .. |downloads_r-numbat| image:: https://img.shields.io/conda/dn/bioconda/r-numbat.svg?style=flat :target: https://anaconda.org/bioconda/r-numbat :alt: (downloads) .. |docker_r-numbat| image:: https://quay.io/repository/biocontainers/r-numbat/status :target: https://quay.io/repository/biocontainers/r-numbat .. _`r-numbat/tags`: https://quay.io/repository/biocontainers/r-numbat?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/r-numbat/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/r-numbat/README.html