The VEP determines the effect of your variants (SNPs, insertions, deletions, CNVs or structural variants) on genes, transcripts, and protein sequence, as well as regulatory regions.

Versions 83, 86, 87
License Apache 2.0


With an activated Bioconda channel (see 2. Set up channels), install with:

conda install variant-effect-predictor

and update with:

conda update variant-effect-predictor


This package installs only the variant effect predictor (VEP) library code. To install data libraries, you can use the ‘’ command installed along with it. For example, to install the VEP library for human hg19/GRCh37 to a directory -a cf -s homo_sapiens -y GRCh37 -c /output/path/to/hg19/vep -species homo_sapiens -version 86_GRCh37 -d /output/path/to/hg19/vep

(note that is renamed from
and from to avoid having generic script names in the PATH)

The convert cache step is not required but improves lookup speeds during runs. See the VEP documentation for more details


A Docker container is available at