:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-cftools' .. highlight: bash bioconductor-cftools ==================== .. conda:recipe:: bioconductor-cftools :replaces_section_title: :noindex: Informatics Tools for Cell\-Free DNA Study :homepage: https://bioconductor.org/packages/3.18/bioc/html/cfTools.html :license: file LICENSE :recipe: /`bioconductor-cftools `_/`meta.yaml `_ The cfTools R package provides methods for cell\-free DNA \(cfDNA\) methylation data analysis to facilitate cfDNA\-based studies. Given the methylation sequencing data of a cfDNA sample\, for each cancer marker or tissue marker\, we deconvolve the tumor\-derived or tissue\-specific reads from all reads falling in the marker region. Our read\-based deconvolution algorithm exploits the pervasiveness of DNA methylation for signal enhancement\, therefore can sensitively identify a trace amount of tumor\-specific or tissue\-specific cfDNA in plasma. cfTools provides functions for \(1\) cancer detection\: sensitively detect tumor\-derived cfDNA and estimate the tumor\-derived cfDNA fraction \(tumor burden\)\; \(2\) tissue deconvolution\: infer the tissue type composition and the cfDNA fraction of multiple tissue types for a plasma cfDNA sample. These functions can serve as foundations for more advanced cfDNA\-based studies\, including cancer diagnosis and disease monitoring. .. conda:package:: bioconductor-cftools |downloads_bioconductor-cftools| |docker_bioconductor-cftools| :versions: ``1.2.0-0``,  ``1.0.0-0`` :depends bioconductor-basilisk: ``>=1.14.0,<1.15.0`` :depends bioconductor-basilisk: ``>=1.14.1,<1.15.0a0`` :depends bioconductor-cftoolsdata: ``>=1.0.0,<1.1.0`` :depends bioconductor-cftoolsdata: ``>=1.0.0,<1.1.0a0`` :depends bioconductor-genomicranges: ``>=1.54.0,<1.55.0`` :depends bioconductor-genomicranges: ``>=1.54.1,<1.55.0a0`` :depends libblas: ``>=3.9.0,<4.0a0`` :depends libgcc-ng: ``>=12`` :depends liblapack: ``>=3.9.0,<4.0a0`` :depends libstdcxx-ng: ``>=12`` :depends r-base: ``>=4.3,<4.4.0a0`` :depends r-bh: :depends r-r.utils: :depends r-rcpp: :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install bioconductor-cftools and update with:: mamba update bioconductor-cftools To create a new environment, run:: mamba create --name myenvname bioconductor-cftools with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/bioconductor-cftools: (see `bioconductor-cftools/tags`_ for valid values for ````) .. |downloads_bioconductor-cftools| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-cftools.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-cftools :alt: (downloads) .. |docker_bioconductor-cftools| image:: https://quay.io/repository/biocontainers/bioconductor-cftools/status :target: https://quay.io/repository/biocontainers/bioconductor-cftools .. _`bioconductor-cftools/tags`: https://quay.io/repository/biocontainers/bioconductor-cftools?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-cftools/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-cftools/README.html