:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-mnem' .. highlight: bash bioconductor-mnem ================= .. conda:recipe:: bioconductor-mnem :replaces_section_title: :noindex: Mixture Nested Effects Models :homepage: https://bioconductor.org/packages/3.18/bioc/html/mnem.html :license: GPL-3 :recipe: /`bioconductor-mnem `_/`meta.yaml `_ Mixture Nested Effects Models \(mnem\) is an extension of Nested Effects Models and allows for the analysis of single cell perturbation data provided by methods like Perturb\-Seq \(Dixit et al.\, 2016\) or Crop\-Seq \(Datlinger et al.\, 2017\). In those experiments each of many cells is perturbed by a knock\-down of a specific gene\, i.e. several cells are perturbed by a knock\-down of gene A\, several by a knock\-down of gene B\, ... and so forth. The observed read\-out has to be multi\-trait and in the case of the Perturb\-\/Crop\-Seq gene are expression profiles for each cell. mnem uses a mixture model to simultaneously cluster the cell population into k clusters and and infer k networks causally linking the perturbed genes for each cluster. The mixture components are inferred via an expectation maximization algorithm. .. conda:package:: bioconductor-mnem |downloads_bioconductor-mnem| |docker_bioconductor-mnem| :versions: .. raw:: html
1.18.0-01.16.0-01.14.0-11.14.0-01.10.0-21.10.0-11.10.0-01.8.0-01.6.5-0 ``1.18.0-0``,  ``1.16.0-0``,  ``1.14.0-1``,  ``1.14.0-0``,  ``1.10.0-2``,  ``1.10.0-1``,  ``1.10.0-0``,  ``1.8.0-0``,  ``1.6.5-0``,  ``1.6.1-0``,  ``1.4.0-0`` .. raw:: html
:depends bioconductor-graph: ``>=1.80.0,<1.81.0`` :depends bioconductor-graph: ``>=1.80.0,<1.81.0a0`` :depends bioconductor-linnorm: ``>=2.26.0,<2.27.0`` :depends bioconductor-linnorm: ``>=2.26.0,<2.27.0a0`` :depends bioconductor-rgraphviz: ``>=2.46.0,<2.47.0`` :depends bioconductor-rgraphviz: ``>=2.46.0,<2.47.0a0`` :depends libblas: ``>=3.9.0,<4.0a0`` :depends libgcc-ng: ``>=12`` :depends liblapack: ``>=3.9.0,<4.0a0`` :depends libstdcxx-ng: ``>=12`` :depends r-base: ``>=4.3,<4.4.0a0`` :depends r-cluster: :depends r-data.table: :depends r-e1071: :depends r-flexclust: :depends r-ggplot2: :depends r-lattice: :depends r-matrixstats: :depends r-naturalsort: :depends r-rcpp: :depends r-rcppeigen: :depends r-snowfall: :depends r-tsne: :depends r-wesanderson: :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install bioconductor-mnem and update with:: mamba update bioconductor-mnem To create a new environment, run:: mamba create --name myenvname bioconductor-mnem with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/bioconductor-mnem: (see `bioconductor-mnem/tags`_ for valid values for ````) .. |downloads_bioconductor-mnem| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-mnem.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-mnem :alt: (downloads) .. |docker_bioconductor-mnem| image:: https://quay.io/repository/biocontainers/bioconductor-mnem/status :target: https://quay.io/repository/biocontainers/bioconductor-mnem .. _`bioconductor-mnem/tags`: https://quay.io/repository/biocontainers/bioconductor-mnem?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-mnem/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-mnem/README.html