:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'bioconductor-mslp' .. highlight: bash bioconductor-mslp ================= .. conda:recipe:: bioconductor-mslp :replaces_section_title: :noindex: Predict synthetic lethal partners of tumour mutations :homepage: https://bioconductor.org/packages/3.20/bioc/html/mslp.html :license: GPL-3 :recipe: /`bioconductor-mslp `_/`meta.yaml `_ An integrated pipeline to predict the potential synthetic lethality partners \(SLPs\) of tumour mutations\, based on gene expression\, mutation profiling and cell line genetic screens data. It has builtd\-in support for data from cBioPortal. The primary SLPs correlating with muations in WT and compensating for the loss of function of mutations are predicted by random forest based methods \(GENIE3\) and Rank Products\, respectively. Genetic screens are employed to identfy consensus SLPs leads to reduced cell viability when perturbed. .. conda:package:: bioconductor-mslp |downloads_bioconductor-mslp| |docker_bioconductor-mslp| :versions: ``1.12.0-0``,  ``1.8.0-0``,  ``1.4.0-0``,  ``1.2.0-0``,  ``1.0.0-0`` :depends on bioconductor-org.hs.eg.db: ``>=3.22.0,<3.23.0`` :depends on bioconductor-rankprod: ``>=3.36.0,<3.37.0`` :depends on r-base: ``>=4.5,<4.6.0a0`` :depends on r-data.table: ``>=1.13.0`` :depends on r-dorng: :depends on r-fmsb: :depends on r-foreach: :depends on r-magrittr: :depends on r-proc: :depends on r-randomforest: :additional platforms: Installation ------------ You need a conda-compatible package manager (currently either `pixi `__, `conda `__, or `micromamba `__) and the Bioconda channel already activated (see :ref:`bioconda_setup`). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda). Pixi """" With pixi_ installed and the Bioconda channel set up (see :ref:`bioconda_setup`), to install globally, run:: pixi global install bioconductor-mslp to add into an existing workspace instead, run:: pixi add bioconductor-mslp In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:: pixi workspace channel add conda-forge pixi workspace channel add bioconda Conda """"" With conda_ installed and the Bioconda channel set up (see :ref:`bioconda_setup`), to install into an existing and activated environment, run:: conda install bioconductor-mslp Alternatively, to install into a new environment, run:: conda create -n envname bioconductor-mslp with ``envname`` being the name of the desired environment. Container """"""""" Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:: docker pull quay.io/biocontainers/bioconductor-mslp: (see `bioconductor-mslp/tags`_ for valid values for ````). Integrated deployment """"""""""""""""""""" Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration. .. _conda: https://conda.io .. _pixi: https://pixi.sh .. |downloads_bioconductor-mslp| image:: https://img.shields.io/conda/dn/bioconda/bioconductor-mslp.svg?style=flat :target: https://anaconda.org/bioconda/bioconductor-mslp :alt: (downloads) .. |docker_bioconductor-mslp| image:: https://quay.io/repository/biocontainers/bioconductor-mslp/status :target: https://quay.io/repository/biocontainers/bioconductor-mslp .. _`bioconductor-mslp/tags`: https://quay.io/repository/biocontainers/bioconductor-mslp?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/bioconductor-mslp/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/bioconductor-mslp/README.html