:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'chexalign' .. highlight: bash chexalign ========= .. conda:recipe:: chexalign :replaces_section_title: :noindex: ChExAlign is used for alignment and quantification of ChIP\-exo crosslinking patterns. :homepage: https://github.com/seqcode/chexalign :license: MIT :recipe: /`chexalign `_/`meta.yaml `_ ChExAlign is a computational framework that aligns ChIP\-exo crosslinking patterns from multiple proteins across a set of regulatory regions\, and which detects and quantifies protein\-DNA crosslinking events within the aligned profiles. The output of the alignment approach is a set of composite profiles that represent the crosslinking signatures of the complex across analyzed regulatory regions. We then use a probabilistic mixture model to deconvolve individual crosslinking events within the aligned ChIP\-exo profiles\, enabling consistent measurements of protein\-DNA crosslinking strengths across multiple proteins. .. conda:package:: chexalign |downloads_chexalign| |docker_chexalign| :versions: ``0.12-1``,  ``0.12-0``,  ``0.11-0`` :depends openjdk: ``>=8`` :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install chexalign and update with:: mamba update chexalign To create a new environment, run:: mamba create --name myenvname chexalign with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/chexalign: (see `chexalign/tags`_ for valid values for ````) .. |downloads_chexalign| image:: https://img.shields.io/conda/dn/bioconda/chexalign.svg?style=flat :target: https://anaconda.org/bioconda/chexalign :alt: (downloads) .. |docker_chexalign| image:: https://quay.io/repository/biocontainers/chexalign/status :target: https://quay.io/repository/biocontainers/chexalign .. _`chexalign/tags`: https://quay.io/repository/biocontainers/chexalign?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/chexalign/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/chexalign/README.html