:orphan: .. only available via index, not via toctree .. title:: Package Recipe 'paralyzer' .. highlight: bash paralyzer ========= .. conda:recipe:: paralyzer :replaces_section_title: :noindex: We developed the PARalyzer algorithm to generate a high resolution map of interaction sites between RNA\-binding proteins and their targets. The algorithm utilizes the deep sequencing reads generated by PAR\-CLIP \(Photoactivatable\-Ribonucleoside\-Enhanced Crosslinking and Immunoprecipitation\) protocol.The use of photoactivatable nucleotides in the PAR\-CLIP protocol results in more efficient crosslinking between the RNA\-binding protein and its target relative to other CLIP methods\; in addition a nucleotide substitution occurs at the site of crosslinking\, providing for single\-nucleotide resolution binding information. PARalyzer utilizes this nucleotide substition in a kernel density estimate classifier to generate the high resolution set of Protein\-RNA interaction sites. :homepage: https://ohlerlab.mdc-berlin.de/software/PARalyzer_85/ :license: PARalyzer is provided for academic use only, if you wish to use it in another setting please contact Uwe Ohler. :recipe: /`paralyzer `_/`meta.yaml `_ :links: biotools: :biotools:`paralyzer` .. conda:package:: paralyzer |downloads_paralyzer| |docker_paralyzer| :versions: ``1.5-3``,  ``1.5-2``,  ``1.5-1``,  ``1.5-0`` :depends openjdk: :requirements: .. rubric:: Installation You need a conda-compatible package manager (currently either `micromamba `_, `mamba `_, or `conda `_) and the Bioconda channel already activated (see :ref:`set-up-channels`). While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see `here `_ for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others. Given that you already have a conda environment in which you want to have this package, install with:: mamba install paralyzer and update with:: mamba update paralyzer To create a new environment, run:: mamba create --name myenvname paralyzer with ``myenvname`` being a reasonable name for the environment (see e.g. the `mamba docs `_ for details and further options). Alternatively, use the docker container:: docker pull quay.io/biocontainers/paralyzer: (see `paralyzer/tags`_ for valid values for ````) .. |downloads_paralyzer| image:: https://img.shields.io/conda/dn/bioconda/paralyzer.svg?style=flat :target: https://anaconda.org/bioconda/paralyzer :alt: (downloads) .. |docker_paralyzer| image:: https://quay.io/repository/biocontainers/paralyzer/status :target: https://quay.io/repository/biocontainers/paralyzer .. _`paralyzer/tags`: https://quay.io/repository/biocontainers/paralyzer?tab=tags .. raw:: html Download stats ----------------- .. raw:: html :file: ../../templates/package_dashboard.html Link to this page ----------------- Render an |install-with-bioconda| badge with the following MarkDown:: [![install with bioconda](https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat)](http://bioconda.github.io/recipes/paralyzer/README.html) .. |install-with-bioconda| image:: https://img.shields.io/badge/install%20with-bioconda-brightgreen.svg?style=flat :target: http://bioconda.github.io/recipes/paralyzer/README.html