- recipe bioconductor-crisprscore
On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
- Homepage:
https://bioconductor.org/packages/3.16/bioc/html/crisprScore.html
- License:
MIT + file LICENSE
- Recipe:
Provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a, enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring methods are RuleSet1, Azimuth, DeepHF, DeepCpf1, enPAM+GB, and CRISPRscan. Both the CFD and MIT scoring methods are available for off-target specificity prediction. The package also provides a Lindel-derived score to predict the probability of a gRNA to produce indels inducing a frameshift for the Cas9 nuclease. Note that DeepHF, DeepCpf1 and enPAM+GB are not available on Windows machines.
- package bioconductor-crisprscore¶
-
- Versions:
1.2.0-0
- Depends:
bioconductor-basilisk
>=1.10.0,<1.11.0
bioconductor-basilisk.utils
>=1.10.0,<1.11.0
bioconductor-biocgenerics
>=0.44.0,<0.45.0
bioconductor-biostrings
>=2.66.0,<2.67.0
bioconductor-crisprscoredata
>=1.2.0,<1.3.0
bioconductor-iranges
>=2.32.0,<2.33.0
bioconductor-xvector
>=0.38.0,<0.39.0
r-base
>=4.2,<4.3.0a0
- Required By:
Installation
With an activated Bioconda channel (see set-up-channels), install with:
conda install bioconductor-crisprscore
and update with:
conda update bioconductor-crisprscore
or use the docker container:
docker pull quay.io/biocontainers/bioconductor-crisprscore:<tag>
(see bioconductor-crisprscore/tags for valid values for
<tag>
)
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-crisprscore/README.html)