recipe bioconductor-differentialregulation

Differentially regulated genes from scRNA-seq data

Homepage:

https://bioconductor.org/packages/3.16/bioc/html/DifferentialRegulation.html

License:

GPL-3

Recipe:

/bioconductor-differentialregulation/meta.yaml

DifferentialRegulation is a method for detecting differentially regulated genes between two groups of samples (e.g., healthy vs. disease, or treated vs. untreated samples), by targeting differences in the balance of spliced and unspliced mRNA abundances, obtained from single-cell RNA-sequencing (scRNA-seq) data. DifferentialRegulation accounts for the sample-to-sample variability, and embeds multiple samples in a Bayesian hierarchical model. In particular, when reads are compatible with multiple genes or multiple splicing versions of a gene (unspliced spliced or ambiguous), the method allocates these multi-mapping reads to the gene of origin and their splicing version. Parameters are inferred via Markov chain Monte Carlo (MCMC) techniques (Metropolis-within-Gibbs).

package bioconductor-differentialregulation

(downloads) docker_bioconductor-differentialregulation

Versions:

1.2.0-0

Depends:
Required By:

Installation

With an activated Bioconda channel (see set-up-channels), install with:

conda install bioconductor-differentialregulation

and update with:

conda update bioconductor-differentialregulation

or use the docker container:

docker pull quay.io/biocontainers/bioconductor-differentialregulation:<tag>

(see bioconductor-differentialregulation/tags for valid values for <tag>)

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