recipe bioconductor-dnea

Differential Network Enrichment Analysis for Biological Data

Homepage:

https://bioconductor.org/packages/3.22/bioc/html/DNEA.html

License:

MIT + file LICENSE

Recipe:

/bioconductor-dnea/meta.yaml

The DNEA R package is the latest implementation of the Differential Network Enrichment Analysis algorithm and is the successor to the Filigree Java-application described in Iyer et al. (2020). The package is designed to take as input an m x n expression matrix for some -omics modality (ie. metabolomics, lipidomics, proteomics, etc.) and jointly estimate the biological network associations of each condition using the DNEA algorithm described in Ma et al. (2019). This approach provides a framework for data-driven enrichment analysis across two experimental conditions that utilizes the underlying correlation structure of the data to determine feature-feature interactions.

package bioconductor-dnea

(downloads) docker_bioconductor-dnea

Versions:

1.0.0-0

Depends:
  • on bioconductor-biocparallel >=1.44.0,<1.45.0

  • on bioconductor-summarizedexperiment >=1.40.0,<1.41.0

  • on r-base >=4.5,<4.6.0a0

  • on r-dplyr

  • on r-gdata

  • on r-glasso

  • on r-igraph >=2.0.3

  • on r-janitor

  • on r-matrix

  • on r-netgsa

  • on r-stringr

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install bioconductor-dnea

to add into an existing workspace instead, run:

pixi add bioconductor-dnea

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install bioconductor-dnea

Alternatively, to install into a new environment, run:

conda create -n envname bioconductor-dnea

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/bioconductor-dnea:<tag>

(see bioconductor-dnea/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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