This is a Hi-C analysis package using a cumulative binomial test to detect interactions between distal genomic loci that have significantly more reads than expected by chance in Hi-C experiments. It takes mapped paired NGS reads as input and gives back the list of significant interactions for a given bin size in the genome.
With an activated Bioconda channel (see 2. Set up channels), install with:
conda install bioconductor-gothic
and update with:
conda update bioconductor-gothic
A Docker container is available at https://quay.io/repository/biocontainers/bioconductor-gothic.