- recipe bioconductor-spicey
Calculates cell type specificity from single cell data
- Homepage:
https://bioconductor.org/packages/3.22/bioc/html/SPICEY.html
- License:
Artistic-2.0
- Recipe:
SPICEY (SPecificity Index for Coding and Epigenetic activitY) is an R package designed to quantify cell-type specificity in single-cell transcriptomic and epigenomic data, particularly scRNA-seq and scATAC-seq. It introduces two complementary indices: the Gene Expression Tissue Specificity Index (GETSI) and the Regulatory Element Tissue Specificity Index (RETSI), both based on entropy to provide continuous, interpretable measures of specificity. By integrating gene expression and chromatin accessibility, SPICEY enables standardized analysis of cell-type-specific regulatory programs across diverse tissues and conditions.
- package bioconductor-spicey¶
-
- Versions:
1.0.0-0- Depends:
on bioconductor-annotationdbi
>=1.72.0,<1.73.0on bioconductor-genomeinfodb
>=1.46.0,<1.47.0on bioconductor-genomicfeatures
>=1.62.0,<1.63.0on bioconductor-genomicranges
>=1.62.0,<1.63.0on bioconductor-s4vectors
>=0.48.0,<0.49.0on r-base
>=4.5,<4.6.0a0on r-cowplot
on r-dplyr
on r-ggplot2
on r-scales
on r-tibble
on r-tidyr
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install bioconductor-spicey
to add into an existing workspace instead, run:
pixi add bioconductor-spicey
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install bioconductor-spicey
Alternatively, to install into a new environment, run:
conda create -n envname bioconductor-spicey
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/bioconductor-spicey:<tag>
(see bioconductor-spicey/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-spicey/README.html)