- recipe bioconductor-synergyfinder
Calculate and Visualize Synergy Scores for Drug Combinations
- Homepage:
https://bioconductor.org/packages/3.16/bioc/html/synergyfinder.html
- License:
Mozilla Public License 2.0
- Recipe:
- Links:
biotools: synergyfinder, doi: 10.1093/bioinformatics/btx162
Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application (https://synergyfinderplus.org/) for users who prefer graphical user interface.
- package bioconductor-synergyfinder¶
-
- Versions:
3.6.0-0
,3.2.2-0
,3.0.3-0
,2.4.10-0
,2.4.0-0
,2.2.0-0
,2.0.1-0
,1.10.2-0
,1.10.0-0
,3.6.0-0
,3.2.2-0
,3.0.3-0
,2.4.10-0
,2.4.0-0
,2.2.0-0
,2.0.1-0
,1.10.2-0
,1.10.0-0
,1.8.0-0
,1.6.1-0
,1.4.0-0
,1.2.0-0
,1.0.0-0
- Depends:
r-base
>=4.2,<4.3.0a0
r-dplyr
>=1.0.3
r-drc
>=3.0-1
r-furrr
>=0.2.2
r-future
>=1.21.0
r-ggforce
>=0.3.2
r-ggplot2
>=3.3.3
r-ggrepel
>=0.9.1
r-gstat
>=2.0-6
r-kriging
>=1.1
r-lattice
>=0.20-41
r-magrittr
>=2.0.1
r-metr
>=0.9.1
r-mice
>=3.13.0
r-nleqslv
>=3.3.2
r-pbapply
>=1.4-3
r-plotly
>=4.9.3
r-purrr
>=0.3.4
r-reshape2
>=1.4.4
r-sp
>=1.4-5
r-spatialextremes
>=2.0-9
r-stringr
>=1.4.0
r-tidyr
>=1.1.2
r-tidyverse
>=1.3.0
r-vegan
>=2.5-7
- Required By:
Installation
With an activated Bioconda channel (see set-up-channels), install with:
conda install bioconductor-synergyfinder
and update with:
conda update bioconductor-synergyfinder
or use the docker container:
docker pull quay.io/biocontainers/bioconductor-synergyfinder:<tag>
(see bioconductor-synergyfinder/tags for valid values for
<tag>
)
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-synergyfinder/README.html)