recipe bioconductor-synergyfinder

Calculate and Visualize Synergy Scores for Drug Combinations



Mozilla Public License 2.0




biotools: synergyfinder, doi: 10.1093/bioinformatics/btx162

Efficient implementations for analyzing pre-clinical multiple drug combination datasets. It provides efficient implementations for 1.the popular synergy scoring models, including HSA, Loewe, Bliss, and ZIP to quantify the degree of drug combination synergy; 2. higher order drug combination data analysis and synergy landscape visualization for unlimited number of drugs in a combination; 3. statistical analysis of drug combination synergy and sensitivity with confidence intervals and p-values; 4. synergy barometer for harmonizing multiple synergy scoring methods to provide a consensus metric of synergy; 5. evaluation of synergy and sensitivity simultaneously to provide an unbiased interpretation of the clinical potential of the drug combinations. Based on this package, we also provide a web application ( for users who prefer graphical user interface.

package bioconductor-synergyfinder

(downloads) docker_bioconductor-synergyfinder



Required By:


With an activated Bioconda channel (see set-up-channels), install with:

conda install bioconductor-synergyfinder

and update with:

conda update bioconductor-synergyfinder

or use the docker container:

docker pull<tag>

(see bioconductor-synergyfinder/tags for valid values for <tag>)

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