recipe chisel

Copy-number Haplotype Inference in Single-cell by Evolutionary Links

Homepage:

https://github.com/raphael-group/chisel

License:

BSD-3

Recipe:

/chisel/meta.yaml

CHISEL is an algorithm to infer allele- and haplotype-specififc copy numbers in individual cells from low-coverage single-cell DNA sequencing data. Specifically, the current implementation of CHISEL has been designed to be diretly applied to ultra-low coverage single-cell DNA sequencing data from 10X Genomics CNV solution, however CHISEL will be adapted to the data generated by any other available technology (e.g. DLP+).

package chisel

(downloads) docker_chisel

Versions:

1.1.4-01.1.3-01.1.2-01.1.1-01.1-01.0.0-00.0.5-00.0.4-00.0.2-0

Depends:
  • on art

  • on bcftools

  • on bwa

  • on gawk

  • on matplotlib-base

  • on numpy >=1.16.1

  • on pandas

  • on python <3

  • on samtools

  • on scipy >=1.2.1

  • on seaborn >=0.7.1,<=0.9.0

  • on statsmodels <=0.10.1

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install chisel

to add into an existing workspace instead, run:

pixi add chisel

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install chisel

Alternatively, to install into a new environment, run:

conda create -n envname chisel

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/chisel:<tag>

(see chisel/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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