recipe pylocuszoom

Publication-ready GWAS visualization library with regional association plots, gene tracks, eQTL, PheWAS, fine-mapping, and forest plots

Homepage:

https://github.com/michael-denyer/pylocuszoom

License:

GPL3 / GPL-3.0-or-later

Recipe:

/pylocuszoom/meta.yaml

pyLocusZoom creates publication-quality genetic association visualizations: regional association plots with LD coloring and recombination overlays, stacked multi-GWAS comparisons, eQTL overlays, fine-mapping/SuSiE credible sets, PheWAS (phenome-wide association) plots, and forest plots for meta-analysis. Includes gene track visualization, file loaders for common formats (REGENIE, BOLT-LMM, SAIGE, GEMMA, GTEx, SuSiE, FINEMAP), and three backends: matplotlib (static/publication), plotly (interactive), and bokeh (dashboards).

package pylocuszoom

(downloads) docker_pylocuszoom

Versions:

1.4.0-01.3.7-01.3.6-01.3.5-01.3.2-01.3.1-01.2.0-01.1.2-01.0.0-0

Depends:
  • on adjusttext >=0.8

  • on bokeh >=3.8.2

  • on colorcet >=3.0.0

  • on loguru >=0.7.0

  • on matplotlib-base >=3.5.0

  • on numpy >=1.21.0

  • on pandas >=1.4.0

  • on plotly >=5.15.0

  • on pydantic >=2.0.0

  • on pyliftover >=0.4

  • on python >=3.10

  • on python-kaleido >=0.2.0

  • on requests >=2.25.0

  • on tqdm >=4.60.0

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install pylocuszoom

to add into an existing workspace instead, run:

pixi add pylocuszoom

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install pylocuszoom

Alternatively, to install into a new environment, run:

conda create -n envname pylocuszoom

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/pylocuszoom:<tag>

(see pylocuszoom/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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