recipe bioconductor-cytoglmm

Conditional Differential Analysis for Flow and Mass Cytometry Experiments

Homepage:

https://bioconductor.org/packages/3.20/bioc/html/CytoGLMM.html

License:

LGPL-3

Recipe:

/bioconductor-cytoglmm/meta.yaml

The CytoGLMM R package implements two multiple regression strategies: A bootstrapped generalized linear model (GLM) and a generalized linear mixed model (GLMM). Most current data analysis tools compare expressions across many computationally discovered cell types. CytoGLMM focuses on just one cell type. Our narrower field of application allows us to define a more specific statistical model with easier to control statistical guarantees. As a result, CytoGLMM finds differential proteins in flow and mass cytometry data while reducing biases arising from marker correlations and safeguarding against false discoveries induced by patient heterogeneity.

package bioconductor-cytoglmm

(downloads) docker_bioconductor-cytoglmm

Versions:

1.18.0-01.14.0-01.10.0-01.8.0-01.6.0-01.2.0-01.0.0-0

Depends:
  • on bioconductor-biocparallel >=1.44.0,<1.45.0

  • on r-base >=4.5,<4.6.0a0

  • on r-caret

  • on r-cowplot

  • on r-doparallel

  • on r-dplyr

  • on r-factoextra

  • on r-flexmix

  • on r-ggplot2

  • on r-ggrepel

  • on r-logging

  • on r-magrittr

  • on r-mass

  • on r-matrix

  • on r-mbest

  • on r-pheatmap

  • on r-rcolorbrewer

  • on r-rlang

  • on r-stringr

  • on r-strucchange

  • on r-tibble

  • on r-tidyr

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install bioconductor-cytoglmm

to add into an existing workspace instead, run:

pixi add bioconductor-cytoglmm

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install bioconductor-cytoglmm

Alternatively, to install into a new environment, run:

conda create -n envname bioconductor-cytoglmm

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/bioconductor-cytoglmm:<tag>

(see bioconductor-cytoglmm/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

Download stats