recipe bioconductor-cytokernel

Differential expression using kernel-based score test

Homepage:

https://bioconductor.org/packages/3.20/bioc/html/cytoKernel.html

License:

GPL-3

Recipe:

/bioconductor-cytokernel/meta.yaml

cytoKernel implements a kernel-based score test to identify differentially expressed features in high-dimensional biological experiments. This approach can be applied across many different high-dimensional biological data including gene expression data and dimensionally reduced cytometry-based marker expression data. In this R package, we implement functions that compute the feature-wise p values and their corresponding adjusted p values. Additionally, it also computes the feature-wise shrunk effect sizes and their corresponding shrunken effect size. Further, it calculates the percent of differentially expressed features and plots user-friendly heatmap of the top differentially expressed features on the rows and samples on the columns.

package bioconductor-cytokernel

(downloads) docker_bioconductor-cytokernel

Versions:

1.16.0-01.12.0-01.8.0-01.6.0-01.4.0-11.4.0-01.0.0-21.0.0-11.0.0-0

Depends:
  • on bioconductor-biocparallel >=1.44.0,<1.45.0

  • on bioconductor-biocparallel >=1.44.0,<1.45.0a0

  • on bioconductor-complexheatmap >=2.26.0,<2.27.0

  • on bioconductor-complexheatmap >=2.26.1,<2.27.0a0

  • on bioconductor-s4vectors >=0.48.0,<0.49.0

  • on bioconductor-s4vectors >=0.48.0,<0.49.0a0

  • on bioconductor-summarizedexperiment >=1.40.0,<1.41.0

  • on bioconductor-summarizedexperiment >=1.40.0,<1.41.0a0

  • on libblas >=3.9.0,<4.0a0

  • on libgcc >=14

  • on liblapack >=3.9.0,<4.0a0

  • on liblzma >=5.8.2,<6.0a0

  • on libstdcxx >=14

  • on libzlib >=1.3.1,<2.0a0

  • on r-ashr

  • on r-base >=4.5,<4.6.0a0

  • on r-circlize

  • on r-data.table

  • on r-dplyr

  • on r-magrittr

  • on r-rcpp

  • on r-rlang

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install bioconductor-cytokernel

to add into an existing workspace instead, run:

pixi add bioconductor-cytokernel

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install bioconductor-cytokernel

Alternatively, to install into a new environment, run:

conda create -n envname bioconductor-cytokernel

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/bioconductor-cytokernel:<tag>

(see bioconductor-cytokernel/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

Download stats