- recipe bioconductor-dar
Differential Abundance Analysis by Consensus
- Homepage:
- License:
MIT + file LICENSE
- Recipe:
Differential abundance testing in microbiome data challenges both parametric and non-parametric statistical methods, due to its sparsity, high variability and compositional nature. Microbiome-specific statistical methods often assume classical distribution models or take into account compositional specifics. These produce results that range within the specificity vs sensitivity space in such a way that type I and type II error that are difficult to ascertain in real microbiome data when a single method is used. Recently, a consensus approach based on multiple differential abundance (DA) methods was recently suggested in order to increase robustness. With dar, you can use dplyr-like pipeable sequences of DA methods and then apply different consensus strategies. In this way we can obtain more reliable results in a fast, consistent and reproducible way.
- package bioconductor-dar¶
-
- Versions:
1.6.0-0,1.2.0-0- Depends:
on bioconductor-complexheatmap
>=2.26.0,<2.27.0on bioconductor-mia
>=1.18.0,<1.19.0on bioconductor-phyloseq
>=1.54.0,<1.55.0on r-base
>=4.5,<4.6.0a0on r-cli
on r-crayon
on r-dplyr
on r-generics
on r-ggplot2
on r-glue
on r-gplots
on r-heatmaply
on r-magrittr
on r-purrr
on r-readr
on r-rlang
>=0.4.11on r-scales
on r-stringr
on r-tibble
on r-tidyr
on r-upsetr
on r-waldo
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install bioconductor-dar
to add into an existing workspace instead, run:
pixi add bioconductor-dar
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install bioconductor-dar
Alternatively, to install into a new environment, run:
conda create -n envname bioconductor-dar
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/bioconductor-dar:<tag>
(see bioconductor-dar/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-dar/README.html)