recipe bioconductor-densvis

Density-Preserving Data Visualization via Non-Linear Dimensionality Reduction

Homepage:

https://bioconductor.org/packages/3.20/bioc/html/densvis.html

License:

MIT + file LICENSE

Recipe:

/bioconductor-densvis/meta.yaml

Implements the density-preserving modification to t-SNE and UMAP described by Narayan et al. (2020) <doi:10.1101/2020.05.12.077776>. The non-linear dimensionality reduction techniques t-SNE and UMAP enable users to summarise complex high-dimensional sequencing data such as single cell RNAseq using lower dimensional representations. These lower dimensional representations enable the visualisation of discrete transcriptional states, as well as continuous trajectory (for example, in early development). However, these methods focus on the local neighbourhood structure of the data. In some cases, this results in misleading visualisations, where the density of cells in the low-dimensional embedding does not represent the transcriptional heterogeneity of data in the original high-dimensional space. den-SNE and densMAP aim to enable more accurate visual interpretation of high-dimensional datasets by producing lower-dimensional embeddings that accurately represent the heterogeneity of the original high-dimensional space, enabling the identification of homogeneous and heterogeneous cell states. This accuracy is accomplished by including in the optimisation process a term which considers the local density of points in the original high-dimensional space. This can help to create visualisations that are more representative of heterogeneity in the original high-dimensional space.

package bioconductor-densvis

(downloads) docker_bioconductor-densvis

Versions:
1.20.1-01.16.0-01.12.0-01.10.2-01.8.0-11.8.0-01.4.0-21.4.0-11.4.0-0

1.20.1-01.16.0-01.12.0-01.10.2-01.8.0-11.8.0-01.4.0-21.4.0-11.4.0-01.2.0-01.00.6-01.0.0-1

Depends:
  • on bioconductor-basilisk >=1.22.0,<1.23.0

  • on bioconductor-basilisk >=1.22.0,<1.23.0a0

  • on libblas >=3.9.0,<4.0a0

  • on libgcc >=14

  • on liblapack >=3.9.0,<4.0a0

  • on liblzma >=5.8.2,<6.0a0

  • on libstdcxx >=14

  • on libzlib >=1.3.1,<2.0a0

  • on r-assertthat

  • on r-base >=4.5,<4.6.0a0

  • on r-irlba

  • on r-rcpp

  • on r-reticulate

  • on r-rtsne

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install bioconductor-densvis

to add into an existing workspace instead, run:

pixi add bioconductor-densvis

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install bioconductor-densvis

Alternatively, to install into a new environment, run:

conda create -n envname bioconductor-densvis

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/bioconductor-densvis:<tag>

(see bioconductor-densvis/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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