- recipe bioconductor-drivernet
Drivernet: uncovering somatic driver mutations modulating transcriptional networks in cancer
- Homepage:
https://bioconductor.org/packages/3.20/bioc/html/DriverNet.html
- License:
GPL-3
- Recipe:
- Links:
biotools: drivernet, doi: 10.1186/gb-2012-13-12-r124
DriverNet is a package to predict functional important driver genes in cancer by integrating genome data (mutation and copy number variation data) and transcriptome data (gene expression data). The different kinds of data are combined by an influence graph, which is a gene-gene interaction network deduced from pathway data. A greedy algorithm is used to find the possible driver genes, which may mutated in a larger number of patients and these mutations will push the gene expression values of the connected genes to some extreme values.
- package bioconductor-drivernet¶
- Versions:
1.50.0-0,1.46.0-0,1.42.0-0,1.40.0-0,1.38.0-0,1.34.0-0,1.32.0-0,1.30.0-1,1.30.0-0,1.50.0-0,1.46.0-0,1.42.0-0,1.40.0-0,1.38.0-0,1.34.0-0,1.32.0-0,1.30.0-1,1.30.0-0,1.28.0-0,1.26.0-0,1.24.0-1,1.24.0-0,1.22.0-0,1.20.0-0,1.18.0-0- Depends:
on r-base
>=4.5,<4.6.0a0
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install bioconductor-drivernet
to add into an existing workspace instead, run:
pixi add bioconductor-drivernet
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install bioconductor-drivernet
Alternatively, to install into a new environment, run:
conda create -n envname bioconductor-drivernet
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/bioconductor-drivernet:<tag>
(see bioconductor-drivernet/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an 
badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-drivernet/README.html)
