recipe bioconductor-generxcluster

gRx Differential Clustering



GPL (>= 2)




biotools: generxcluster

Detect Differential Clustering of Genomic Sites such as gene therapy integrations. The package provides some functions for exploring genomic insertion sites originating from two different sources. Possibly, the two sources are two different gene therapy vectors. Vectors are preferred that target sensitive regions less frequently, motivating the search for localized clusters of insertions and comparison of the clusters formed by integration of different vectors. Scan statistics allow the discovery of spatial differences in clustering and calculation of False Discovery Rates (FDRs) providing statistical methods for comparing retroviral vectors. A scan statistic for comparing two vectors using multiple window widths to detect clustering differentials and compute FDRs is implemented here.

package bioconductor-generxcluster

(downloads) docker_bioconductor-generxcluster



depends bioconductor-genomicranges:


depends bioconductor-iranges:


depends libblas:


depends libgcc-ng:


depends liblapack:


depends r-base:




You need a conda-compatible package manager (currently either micromamba, mamba, or conda) and the Bioconda channel already activated (see set-up-channels).

While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see here for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others.

Given that you already have a conda environment in which you want to have this package, install with:

   mamba install bioconductor-generxcluster

and update with::

   mamba update bioconductor-generxcluster

To create a new environment, run:

mamba create --name myenvname bioconductor-generxcluster

with myenvname being a reasonable name for the environment (see e.g. the mamba docs for details and further options).

Alternatively, use the docker container:

   docker pull<tag>

(see `bioconductor-generxcluster/tags`_ for valid values for ``<tag>``)

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