- recipe bioconductor-genesis
GENetic EStimation and Inference in Structured samples (GENESIS): Statistical methods for analyzing genetic data from samples with population structure and/or relatedness
- Homepage:
https://bioconductor.org/packages/3.20/bioc/html/GENESIS.html
- License:
GPL-3
- Recipe:
The GENESIS package provides methodology for estimating, inferring, and accounting for population and pedigree structure in genetic analyses. The current implementation provides functions to perform PC-AiR (Conomos et al., 2015, Gen Epi) and PC-Relate (Conomos et al., 2016, AJHG). PC-AiR performs a Principal Components Analysis on genome-wide SNP data for the detection of population structure in a sample that may contain known or cryptic relatedness. Unlike standard PCA, PC-AiR accounts for relatedness in the sample to provide accurate ancestry inference that is not confounded by family structure. PC-Relate uses ancestry representative principal components to adjust for population structure/ancestry and accurately estimate measures of recent genetic relatedness such as kinship coefficients, IBD sharing probabilities, and inbreeding coefficients. Additionally, functions are provided to perform efficient variance component estimation and mixed model association testing for both quantitative and binary phenotypes.
- package bioconductor-genesis¶
-
- Versions:
2.40.0-1,2.40.0-0,2.36.0-0,2.32.0-0,2.30.0-0,2.28.0-1,2.28.0-0,2.24.2-0,2.24.1-0,2.40.0-1,2.40.0-0,2.36.0-0,2.32.0-0,2.30.0-0,2.28.0-1,2.28.0-0,2.24.2-0,2.24.1-0,2.24.0-0,2.22.1-0,2.20.1-0,2.20.0-0,2.18.0-0,2.16.0-0,2.14.3-0,2.12.0-0- Depends:
on bioconductor-biobase
>=2.70.0,<2.71.0on bioconductor-biobase
>=2.70.0,<2.71.0a0on bioconductor-biocgenerics
>=0.56.0,<0.57.0on bioconductor-biocgenerics
>=0.56.0,<0.57.0a0on bioconductor-biocparallel
>=1.44.0,<1.45.0on bioconductor-biocparallel
>=1.44.0,<1.45.0a0on bioconductor-gdsfmt
>=1.46.0,<1.47.0on bioconductor-gdsfmt
>=1.46.0,<1.47.0a0on bioconductor-genomicranges
>=1.62.0,<1.63.0on bioconductor-genomicranges
>=1.62.1,<1.63.0a0on bioconductor-gwastools
>=1.56.0,<1.57.0on bioconductor-gwastools
>=1.56.0,<1.57.0a0on bioconductor-iranges
>=2.44.0,<2.45.0on bioconductor-iranges
>=2.44.0,<2.45.0a0on bioconductor-s4vectors
>=0.48.0,<0.49.0on bioconductor-s4vectors
>=0.48.0,<0.49.0a0on bioconductor-seqarray
>=1.50.0,<1.51.0on bioconductor-seqarray
>=1.50.1,<1.51.0a0on bioconductor-seqvartools
>=1.48.0,<1.49.0on bioconductor-seqvartools
>=1.48.0,<1.49.0a0on bioconductor-snprelate
>=1.44.0,<1.45.0on bioconductor-snprelate
>=1.44.0,<1.45.0a0on libblas
>=3.9.0,<4.0a0on libgcc
>=14on liblapack
>=3.9.0,<4.0a0on liblzma
>=5.8.2,<6.0a0on libopenblas
>=0.3.31,<1.0a0on libzlib
>=1.3.1,<2.0a0on r-base
>=4.5,<4.6.0a0on r-data.table
on r-igraph
on r-matrix
on r-reshape2
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install bioconductor-genesis
to add into an existing workspace instead, run:
pixi add bioconductor-genesis
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install bioconductor-genesis
Alternatively, to install into a new environment, run:
conda create -n envname bioconductor-genesis
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/bioconductor-genesis:<tag>
(see bioconductor-genesis/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-genesis/README.html)