recipe bioconductor-gofuncr

GOfuncR performs a gene ontology enrichment analysis based on the ontology enrichment software FUNC. GO-annotations are obtained from OrganismDb or OrgDb packages (‘Homo.sapiens’ by default); the GO-graph is included in the package and updated regularly (27-Mar-2019). GOfuncR provides the standard candidate vs. background enrichment analysis using the hypergeometric test, as well as three additional tests: (i) the Wilcoxon rank-sum test that is used when genes are ranked, (ii) a binomial test that is used when genes are associated with two counts and (iii) a Chi-square or Fisher’s exact test that is used in cases when genes are associated with four counts. To correct for multiple testing and interdependency of the tests, family-wise error rates are computed based on random permutations of the gene-associated variables. GOfuncR also provides tools for exploring the ontology graph and the annotations, and options to take gene-length or spatial clustering of genes into account. It is also possible to provide custom gene coordinates, annotations and ontologies.



GPL (>= 2)



package bioconductor-gofuncr

(downloads) docker_bioconductor-gofuncr



Required By


With an activated Bioconda channel (see 2. Set up channels), install with:

conda install bioconductor-gofuncr

and update with:

conda update bioconductor-gofuncr

or use the docker container:

docker pull<tag>

(see bioconductor-gofuncr/tags for valid values for <tag>)