- recipe bioconductor-ifaa
Robust Inference for Absolute Abundance in Microbiome Analysis
- Homepage:
- License:
GPL-2
- Recipe:
This package offers a robust approach to make inference on the association of covariates with the absolute abundance (AA) of microbiome in an ecosystem. It can be also directly applied to relative abundance (RA) data to make inference on AA because the ratio of two RA is equal to the ratio of their AA. This algorithm can estimate and test the associations of interest while adjusting for potential confounders. The estimates of this method have easy interpretation like a typical regression analysis. High-dimensional covariates are handled with regularization and it is implemented by parallel computing. False discovery rate is automatically controlled by this approach. Zeros do not need to be imputed by a positive value for the analysis. The IFAA package also offers the 'MZILN' function for estimating and testing associations of abundance ratios with covariates.
- package bioconductor-ifaa¶
-
- Versions:
1.12.0-0,1.8.0-0,1.4.0-0,1.2.0-0- Depends:
on bioconductor-s4vectors
>=0.48.0,<0.49.0on bioconductor-summarizedexperiment
>=1.40.0,<1.41.0on r-base
>=4.5,<4.6.0a0on r-desctools
on r-doparallel
>=1.0.11on r-dorng
on r-foreach
>=1.4.3on r-glmnet
on r-hdci
>=1.0-2on r-mathjaxr
on r-matrix
>=1.4-0on r-matrixextra
on r-parallelly
on r-stringr
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install bioconductor-ifaa
to add into an existing workspace instead, run:
pixi add bioconductor-ifaa
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install bioconductor-ifaa
Alternatively, to install into a new environment, run:
conda create -n envname bioconductor-ifaa
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/bioconductor-ifaa:<tag>
(see bioconductor-ifaa/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-ifaa/README.html)