- recipe bioconductor-mixomics
Omics Data Integration Project
- Homepage:
https://bioconductor.org/packages/3.20/bioc/html/mixOmics.html
- License:
GPL (>= 2)
- Recipe:
Multivariate methods are well suited to large omics data sets where the number of variables (e.g. genes, proteins, metabolites) is much larger than the number of samples (patients, cells, mice). They have the appealing properties of reducing the dimension of the data by using instrumental variables (components), which are defined as combinations of all variables. Those components are then used to produce useful graphical outputs that enable better understanding of the relationships and correlation structures between the different data sets that are integrated. mixOmics offers a wide range of multivariate methods for the exploration and integration of biological datasets with a particular focus on variable selection. The package proposes several sparse multivariate models we have developed to identify the key variables that are highly correlated, and/or explain the biological outcome of interest. The data that can be analysed with mixOmics may come from high throughput sequencing technologies, such as omics data (transcriptomics, metabolomics, proteomics, metagenomics etc) but also beyond the realm of omics (e.g. spectral imaging). The methods implemented in mixOmics can also handle missing values without having to delete entire rows with missing data. A non exhaustive list of methods include variants of generalised Canonical Correlation Analysis, sparse Partial Least Squares and sparse Discriminant Analysis. Recently we implemented integrative methods to combine multiple data sets: N-integration with variants of Generalised Canonical Correlation Analysis and P-integration with variants of multi-group Partial Least Squares.
- package bioconductor-mixomics¶
-
- Versions:
6.34.0-0,6.30.0-0,6.26.0-0,6.24.0-0,6.22.0-0,6.17.26-0,6.16.0-0,6.14.0-1,6.14.0-0,6.34.0-0,6.30.0-0,6.26.0-0,6.24.0-0,6.22.0-0,6.17.26-0,6.16.0-0,6.14.0-1,6.14.0-0,6.12.0-0,6.10.1-0,6.8.0-1,6.8.0-0,6.6.2-0,6.6.0-0- Depends:
on bioconductor-biocparallel
>=1.44.0,<1.45.0on r-base
>=4.5,<4.6.0a0on r-corpcor
on r-dplyr
on r-ellipse
on r-ggplot2
on r-ggrepel
on r-gridextra
on r-gsignal
on r-igraph
on r-lattice
on r-mass
on r-matrixstats
on r-rarpack
on r-rcolorbrewer
on r-reshape2
on r-rgl
on r-tidyr
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install bioconductor-mixomics
to add into an existing workspace instead, run:
pixi add bioconductor-mixomics
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install bioconductor-mixomics
Alternatively, to install into a new environment, run:
conda create -n envname bioconductor-mixomics
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/bioconductor-mixomics:<tag>
(see bioconductor-mixomics/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-mixomics/README.html)