recipe bioconductor-norce

NoRCE: Noncoding RNA Sets Cis Annotation and Enrichment






While some non-coding RNAs (ncRNAs) have been found to play critical regulatory roles in biological processes, most remain functionally uncharacterized. This presents a challenge whenever an interesting set of ncRNAs set needs to be analyzed in a functional context. Transcripts located close-by on the genome are often regulated together, and this spatial proximity hints at a functional association. Based on this idea, we present an R package, NoRCE, that performs cis enrichment analysis for a given set of ncRNAs. Enrichment is carried out by using the functional annotations of the coding genes located proximally to the input ncRNAs. NoRCE allows incorporating other biological information such as the topologically associating domain (TAD) regions, co-expression patterns, and miRNA target information. NoRCE repository includes several data files, such as cell line specific TAD regions, functional gene sets, and cancer expression data. Additionally, users can input custom data files. Results can be retrieved in a tabular format or viewed as graphs. NoRCE is currently available for the following species: human, mouse, rat, zebrafish, fruit fly, worm and yeast.

package bioconductor-norce

(downloads) docker_bioconductor-norce



Required By


With an activated Bioconda channel (see 2. Set up channels), install with:

conda install bioconductor-norce

and update with:

conda update bioconductor-norce

or use the docker container:

docker pull<tag>

(see bioconductor-norce/tags for valid values for <tag>)

Download stats