- recipe bioconductor-normalize450k
Preprocessing of Illumina Infinium 450K data
- Homepage
https://bioconductor.org/packages/3.14/bioc/html/normalize450K.html
- License
BSD_2_clause + file LICENSE
- Recipe
Precise measurements are important for epigenome-wide studies investigating DNA methylation in whole blood samples, where effect sizes are expected to be small in magnitude. The 450K platform is often affected by batch effects and proper preprocessing is recommended. This package provides functions to read and normalize 450K '.idat' files. The normalization corrects for dye bias and biases related to signal intensity and methylation of probes using local regression. No adjustment for probe type bias is performed to avoid the trade-off of precision for accuracy of beta-values.
- package bioconductor-normalize450k¶
-
- Versions
1.22.0-0
,1.20.0-0
,1.18.0-1
,1.18.0-0
,1.16.0-0
,1.14.0-0
,1.12.0-1
,1.10.0-0
- Depends
bioconductor-biobase
>=2.54.0,<2.55.0
bioconductor-illuminaio
>=0.36.0,<0.37.0
r-base
>=4.1,<4.2.0a0
- Required By
Installation
With an activated Bioconda channel (see 2. Set up channels), install with:
conda install bioconductor-normalize450k
and update with:
conda update bioconductor-normalize450k
or use the docker container:
docker pull quay.io/biocontainers/bioconductor-normalize450k:<tag>
(see bioconductor-normalize450k/tags for valid values for
<tag>
)
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/bioconductor-normalize450k/README.html)