recipe bioconductor-pepsettest

Peptide Set Test

Homepage:

https://bioconductor.org/packages/3.20/bioc/html/PepSetTest.html

License:

GPL (>= 3)

Recipe:

/bioconductor-pepsettest/meta.yaml

Peptide Set Test (PepSetTest) is a peptide-centric strategy to infer differentially expressed proteins in LC-MS/MS proteomics data. This test detects coordinated changes in the expression of peptides originating from the same protein and compares these changes against the rest of the peptidome. Compared to traditional aggregation-based approaches, the peptide set test demonstrates improved statistical power, yet controlling the Type I error rate correctly in most cases. This test can be valuable for discovering novel biomarkers and prioritizing drug targets, especially when the direct application of statistical analysis to protein data fails to provide substantial insights.

package bioconductor-pepsettest

(downloads) docker_bioconductor-pepsettest

Versions:

1.4.0-01.0.0-0

Depends:
  • on bioconductor-limma >=3.66.0,<3.67.0

  • on bioconductor-summarizedexperiment >=1.40.0,<1.41.0

  • on r-base >=4.5,<4.6.0a0

  • on r-dplyr

  • on r-lme4

  • on r-mass

  • on r-matrixstats

  • on r-reshape2

  • on r-tibble

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install bioconductor-pepsettest

to add into an existing workspace instead, run:

pixi add bioconductor-pepsettest

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install bioconductor-pepsettest

Alternatively, to install into a new environment, run:

conda create -n envname bioconductor-pepsettest

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/bioconductor-pepsettest:<tag>

(see bioconductor-pepsettest/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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