recipe bioconductor-rnaagecalc

A multi-tissue transcriptional age calculator






It has been shown that both DNA methylation and RNA transcription are linked to chronological age and age related diseases. Several estimators have been developed to predict human aging from DNA level and RNA level. Most of the human transcriptional age predictor are based on microarray data and limited to only a few tissues. To date, transcriptional studies on aging using RNASeq data from different human tissues is limited. The aim of this package is to provide a tool for across-tissue and tissue-specific transcriptional age calculation based on GTEx RNASeq data.

package bioconductor-rnaagecalc

(downloads) docker_bioconductor-rnaagecalc



depends bioconductor-annotationdbi:


depends bioconductor-impute:




depends bioconductor-recount:


depends bioconductor-summarizedexperiment:


depends r-base:


depends r-ggplot2:



You need a conda-compatible package manager (currently either micromamba, mamba, or conda) and the Bioconda channel already activated (see set-up-channels).

While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see here for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others.

Given that you already have a conda environment in which you want to have this package, install with:

   mamba install bioconductor-rnaagecalc

and update with::

   mamba update bioconductor-rnaagecalc

To create a new environment, run:

mamba create --name myenvname bioconductor-rnaagecalc

with myenvname being a reasonable name for the environment (see e.g. the mamba docs for details and further options).

Alternatively, use the docker container:

   docker pull<tag>

(see `bioconductor-rnaagecalc/tags`_ for valid values for ``<tag>``)

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