recipe bioconductor-scan.upc

Single-channel array normalization (SCAN) and Universal exPression Codes (UPC)







biotools: scan.upc

SCAN is a microarray normalization method to facilitate personalized-medicine workflows. Rather than processing microarray samples as groups, which can introduce biases and present logistical challenges, SCAN normalizes each sample individually by modeling and removing probe- and array-specific background noise using only data from within each array. SCAN can be applied to one-channel (e.g., Affymetrix) or two-channel (e.g., Agilent) microarrays. The Universal exPression Codes (UPC) method is an extension of SCAN that estimates whether a given gene/transcript is active above background levels in a given sample. The UPC method can be applied to one-channel or two-channel microarrays as well as to RNA-Seq read counts. Because UPC values are represented on the same scale and have an identical interpretation for each platform, they can be used for cross-platform data integration.

package bioconductor-scan.upc

(downloads) docker_bioconductor-scan.upc



Required By


With an activated Bioconda channel (see 2. Set up channels), install with:

conda install bioconductor-scan.upc

and update with:

conda update bioconductor-scan.upc

or use the docker container:

docker pull<tag>

(see bioconductor-scan.upc/tags for valid values for <tag>)