recipe bioconductor-scddboost

A compositional model to assess expression changes from single-cell rna-seq data

Homepage:

https://bioconductor.org/packages/3.20/bioc/html/scDDboost.html

License:

GPL (>= 2)

Recipe:

/bioconductor-scddboost/meta.yaml

scDDboost is an R package to analyze changes in the distribution of single-cell expression data between two experimental conditions. Compared to other methods that assess differential expression, scDDboost benefits uniquely from information conveyed by the clustering of cells into cellular subtypes. Through a novel empirical Bayesian formulation it calculates gene-specific posterior probabilities that the marginal expression distribution is the same (or different) between the two conditions. The implementation in scDDboost treats gene-level expression data within each condition as a mixture of negative binomial distributions.

package bioconductor-scddboost

(downloads) docker_bioconductor-scddboost

Versions:

1.12.0-01.4.0-01.2.0-01.0.0-11.0.0-0

Depends:
  • on bioconductor-biocparallel >=1.44.0,<1.45.0

  • on bioconductor-biocparallel >=1.44.0,<1.45.0a0

  • on bioconductor-ebseq >=2.8.0,<2.9.0

  • on bioconductor-ebseq >=2.8.0,<2.9.0a0

  • on bioconductor-oscope >=1.40.0,<1.41.0

  • on bioconductor-oscope >=1.40.0,<1.41.0a0

  • on bioconductor-singlecellexperiment >=1.32.0,<1.33.0

  • on bioconductor-singlecellexperiment >=1.32.0,<1.33.0a0

  • on bioconductor-summarizedexperiment >=1.40.0,<1.41.0

  • on bioconductor-summarizedexperiment >=1.40.0,<1.41.0a0

  • on libblas >=3.9.0,<4.0a0

  • on libgcc >=14

  • on liblapack >=3.9.0,<4.0a0

  • on liblzma >=5.8.2,<6.0a0

  • on libstdcxx >=14

  • on libzlib >=1.3.1,<2.0a0

  • on r-base >=4.5,<4.6.0a0

  • on r-bh

  • on r-cluster

  • on r-ggplot2

  • on r-mclust

  • on r-rcpp >=0.12.11

  • on r-rcppeigen >=0.3.2.9.0

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install bioconductor-scddboost

to add into an existing workspace instead, run:

pixi add bioconductor-scddboost

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install bioconductor-scddboost

Alternatively, to install into a new environment, run:

conda create -n envname bioconductor-scddboost

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/bioconductor-scddboost:<tag>

(see bioconductor-scddboost/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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