- recipe chexmix
ChExMix aims to characterize protein-DNA binding subtypes in ChIP-exo experiments. ChExMix assumes that different regulatory complexes will result in different protein-DNA crosslinking signatures in ChIP-exo data, and thus analysis of ChIP-exo sequencing tag patterns should enable detection of multiple protein-DNA binding modes for a given regulatory protein. ChExMix uses a mixture modeling framework to probabilistically model the genomic locations and subtype membership of protein-DNA binding events, leveraging both ChIP-exo tag enrichment patterns and DNA sequence information. In doing so, ChExMix offers a more principled and robust approach to characterizing binding subtypes than simply clustering binding events using motif information.
- Homepage:
- License:
MIT
- Recipe:
- package chexmix¶
-
- Versions:
0.52-0,0.51-0,0.45-0,0.5-1,0.5-0,0.4-0- Depends:
on meme
>=4.11.2on openjdk
>=8
- Additional platforms:
Installation¶
You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).
Pixi¶
With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:
pixi global install chexmix
to add into an existing workspace instead, run:
pixi add chexmix
In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:
pixi workspace channel add conda-forge
pixi workspace channel add bioconda
Conda¶
With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:
conda install chexmix
Alternatively, to install into a new environment, run:
conda create -n envname chexmix
with envname being the name of the desired environment.
Container¶
Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:
docker pull quay.io/biocontainers/chexmix:<tag>
(see chexmix/tags for valid values for <tag>).
Integrated deployment¶
Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.
Download stats¶
Link to this page¶
Render an badge with the following MarkDown:
[](http://bioconda.github.io/recipes/chexmix/README.html)