recipe cleaverna

Computational tool for scoring candidate cleavage sites of DNAzyme

Homepage:

https://github.com/reyhaneh-tavakoli/CleaveRNA

Documentation:

https://github.com/reyhaneh-tavakoli/CleaveRNA/blob/main/README.md

License:

MIT / MIT

Recipe:

/cleaverna/meta.yaml

CleaveRNA is Advanced machine learning-based computational tool for scoring candidate DNAzyme cleavage sites in substrate RNA sequences using structural and thermodynamic features. The tool supports multiple analysis modes including training and prediction. Key features: - Machine learning-based cleavage site prediction - Multiple prediction modes for different use cases - Feature extraction and model training capabilities - Cross-validation and performance metrics - Single command-line interface for all workflows

package cleaverna

(downloads) docker_cleaverna

Versions:

1.0.0-0

Depends:
  • on intarna >=3.0

  • on matplotlib-base >=3.3.0

  • on numpy >=1.20.0

  • on pandas >=1.3.0

  • on python >=3.7

  • on scikit-learn >=1.0.0

  • on tqdm >=4.60.0

  • on viennarna

Additional platforms:

Installation

You need a conda-compatible package manager (currently either pixi, conda, or micromamba) and the Bioconda channel already activated (see Usage). Below, we show how to install with either pixi or conda (for micromamba and mamba, commands are essentially the same as with conda).

Pixi

With pixi installed and the Bioconda channel set up (see Usage), to install globally, run:

pixi global install cleaverna

to add into an existing workspace instead, run:

pixi add cleaverna

In the latter case, make sure to first add bioconda and conda-forge to the channels considered by the workspace:

pixi workspace channel add conda-forge
pixi workspace channel add bioconda

Conda

With conda installed and the Bioconda channel set up (see Usage), to install into an existing and activated environment, run:

conda install cleaverna

Alternatively, to install into a new environment, run:

conda create -n envname cleaverna

with envname being the name of the desired environment.

Container

Alternatively, every Bioconda package is available as a container image for usage with your preferred container runtime. For e.g. docker, run:

docker pull quay.io/biocontainers/cleaverna:<tag>

(see cleaverna/tags for valid values for <tag>).

Integrated deployment

Finally, note that many scientific workflow management systems directly integrate both conda and container based software deployment. Thus, workflow steps can be often directly annotated to use the package, leading to automatic deployment by the respective workflow management system, thereby improving reproducibility and transparency. Check the documentation of your workflow management system to find out about the integration.

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