SearchGUI is a user-friendly open-source graphical user interface for configuring and running proteomics identification search engines, currently supporting X!Tandem, MS-GF+, MS Amanda, MyriMatch, Comet, Tide, Andromeda and OMSSA.

Versions 3.3.10, 3.3.9, 3.3.6, 3.3.5, 3.3.3, 3.3.1, 3.2.26, 3.2.24, 3.2.20, 3.2.13, 3.2.11, 3.2.8, 3.2.7, 3.2.6, 3.2.5, 3.2.3, 3.1.4, 2.9.0, 2.1.4
License Apache License, Version 2.0
Links biotools: searchgui, doi: 10.1002/pmic.201000595


With an activated Bioconda channel (see 2. Set up channels), install with:

conda install searchgui

and update with:

conda update searchgui


SearchGUI is Java program that comes with a custom wrapper shell script. This shell wrapper is called “opsin” and is on $PATH by default. By default “-Xms512m -Xmx1g” is set in the wrapper. If you want to overwrite it you can specify these values directly after your binaries. If you have _JAVA_OPTIONS set globally this will take precedence. For example run it with “searchgui -Xms512m -Xmx1g”


A Docker container is available at