recipe bioconductor-mdp

Molecular Degree of Perturbation calculates scores for transcriptome data samples based on their perturbation from controls

Homepage:

https://bioconductor.org/packages/3.18/bioc/html/mdp.html

License:

GPL-3

Recipe:

/bioconductor-mdp/meta.yaml

The Molecular Degree of Perturbation webtool quantifies the heterogeneity of samples. It takes a data.frame of omic data that contains at least two classes (control and test) and assigns a score to all samples based on how perturbed they are compared to the controls. It is based on the Molecular Distance to Health (Pankla et al. 2009), and expands on this algorithm by adding the options to calculate the z-score using the modified z-score (using median absolute deviation), change the z-score zeroing threshold, and look at genes that are most perturbed in the test versus control classes.

package bioconductor-mdp

(downloads) docker_bioconductor-mdp

versions:
1.22.0-01.20.0-01.18.0-01.14.0-01.12.0-01.10.0-11.10.0-01.8.0-01.6.0-0

1.22.0-01.20.0-01.18.0-01.14.0-01.12.0-01.10.0-11.10.0-01.8.0-01.6.0-01.4.0-11.4.0-01.2.0-0

depends r-base:

>=4.3,<4.4.0a0

depends r-ggplot2:

depends r-gridextra:

requirements:

Installation

You need a conda-compatible package manager (currently either micromamba, mamba, or conda) and the Bioconda channel already activated (see set-up-channels).

While any of above package managers is fine, it is currently recommended to use either micromamba or mamba (see here for installation instructions). We will show all commands using mamba below, but the arguments are the same for the two others.

Given that you already have a conda environment in which you want to have this package, install with:

   mamba install bioconductor-mdp

and update with::

   mamba update bioconductor-mdp

To create a new environment, run:

mamba create --name myenvname bioconductor-mdp

with myenvname being a reasonable name for the environment (see e.g. the mamba docs for details and further options).

Alternatively, use the docker container:

   docker pull quay.io/biocontainers/bioconductor-mdp:<tag>

(see `bioconductor-mdp/tags`_ for valid values for ``<tag>``)

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